FDA-Approved · Available in Milford, CT

When nothing else
has worked.

Spravato® (esketamine) is a breakthrough nasal spray treatment for adults with treatment-resistant depression. If two or more antidepressants haven't helped, there's another option — and we offer it here.

FDA-Approved for Treatment-Resistant Depression
Covered by Aetna, Anthem, Cigna & United Healthcare
Physician-Led, In-Office Sessions in Milford
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Is This You?

You've tried. It just hasn't worked.

Spravato is designed for people who have already tried antidepressants — and found they weren't enough. If any of these sound familiar, you may be a candidate:

  • You've tried two or more antidepressants without meaningful relief
  • You've spent months — sometimes years — adjusting doses and trying new medications
  • Depression is still significantly affecting your work, relationships, or daily life
  • You're ready to try something that works differently

Spravato targets the glutamate system — a completely different pathway than traditional antidepressants — and many patients notice a difference within hours of their first session.

What to Expect

A structured, supervised treatment.

Every session takes place in our Milford office. You self-administer the nasal spray under direct medical supervision, then rest in a comfortable monitored setting for about 2 hours before being cleared to leave. You'll need a ride home.

Weeks 1–4
Induction
Two sessions per week. This phase builds the foundation — most patients begin noticing changes here.
Weeks 5–8
Optimization
One session per week. Your care team monitors your response and adjusts the plan as needed.
Ongoing
Maintenance
Frequency is tailored to you — some patients continue weekly, others taper as they stabilize.
During each session you may experience mild dissociation or drowsiness — this is expected, temporary, and why every session is medically supervised. Most patients describe it as manageable and short-lived.
Why CMHS

Spravato works best alongside therapy.
Here, both happen under one roof.

Most Spravato providers are psychiatry-only practices. At CMHS, the psychiatrist prescribing your Spravato and your therapist are on the same care team — talking to each other, coordinating your treatment, and adjusting the plan together.

Certified Spravato Treatment Center
We meet all REMS program requirements for Spravato administration — your safety and care are fully protocol-compliant.
Coordinated care — not a referral network
Your psychiatrist, therapist, and APRN work together in the same practice. You never have to repeat your history or chase down records.
Same-week consultations available
We move quickly. If Spravato is right for you, we work to get your first session scheduled without a long wait.
Insurance & Next Steps

Covered by most major plans.

Spravato is covered by most major insurance plans. We verify your benefits before your first session so there are no surprises.

AetnaAnthemCignaUnited Healthcare
Request a Spravato Consultation →

Or call us directly: (203) 651-5117